Ligand Name : |
Quercetin |
Systematic Names : |
Quercetin; Sophoretin; Meletin; Xanthaurine; Quercetine |
Molecular Formula : |
C15H10O7 |
Molecular Weight : |
g/mol |
IUPAC Name : |
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one |
Canonical SMILES : |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
Ligand Description : |
Quercetin is a plant pigment (flavonoid). It is found in many plants and foods, such as red wine, onions, green tea, apples, berries, Ginkgo biloba, St. John's wort, American elder, and others. Buckwheat tea has a large amount of quercetin. People use quercetin as a medicine.
Quercetin is used for treating conditions of the heart and blood vessels including “hardening of the arteries” (atherosclerosis), high cholesterol, heart disease, and circulation problems. It is also used for diabetes, cataracts, hay fever, peptic ulcer, schizophrenia, inflammation, asthma, gout, viral infections, chronic fatigue syndrome (CFS), preventing cancer, and for treating chronic infections of the prostate. Quercetin is also used to increase endurance and improve athletic performance.
Quercetin is a polyphenolic flavonoid with potential chemopreventive activity. Quercetin, ubiquitous in plant food sources and a major bioflavonoid in the human diet, may produce antiproliferative effects resulting from the modulation of either EGFR or estrogen-receptor mediated signal transduction pathways. Although the mechanism of action of action is not fully known, the following effects have been described with this agent in vitro: decreased expression of mutant p53 protein and p21-ras oncogene, induction of cell cycle arrest at the G1 phase and inhibition of heat shock protein synthesis. This compound also demonstrates synergy and reversal of the multidrug resistance phenotype, when combined with chemotherapeutic drugs, in vitro. Quercetin also produces anti-inflammatory and anti-allergy effects mediated through the inhibition of the lipoxygenase and cyclooxygenase pathways, thereby preventing the production of pro-inflammatory mediators. |
Other Related Plants : |
Adhatoda, Apple, Black Pepper, Eucalyptus, Jamun, Lady's Finger, Mango, Neem, Onion, Tomato, Valerian |
Ligand Related Dockings : |
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Plant Name : |
Kandankathiri |
Alternative Names : |
Solanum Xanthocarpum, Kateli, Kandakarichunda, Kandankattiri, Indian Solanum, கண்டங்கத்திரி, முள்கத்திரி |
Scientific Name : |
Solanum Indicum |
Medicinal Parts : |
Fruit, Leaf, Root, Seed, Flower |
Plant Category : |
Herb |
2° Metabolites (4/20) : |
Acetylcholine, Apigenin, Caffeic acid, Carpesterol, Chronogenic acid, Diosgenin, Fatty acid, Histamine, Isochlorogenic acid, Lanosterol, Neochronogenic acid, Potassium Nitrate, Quercetin, β-Sitosterol, Solamargine, Solanocarpidine, Solanocarpine, Solasodine, Solasonine, Tomatidenol |
Phytochemical IDs : |
pdtdbl00105, pdtdbl00070, pdtdbl00038, pdtdbl00027 |
Plant Keywords : |
Kandankathiri, Solanum Indicum, Solanum Xanthocarpum, Kateli, Kandakarichunda, Kandankattiri, Indian Solanum, கண்டங்கத்திரி, முள்கத்திரி |
Plant Description : |
- Solanum xanthocarpum is useful in treating worms, cold, hoarseness of voice, fever, dysuria, enlargement of the liver, muscular pain, spleen and stone in the urinary bladder.
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Nasal administration of Solanum xanthocarpum is beneficial in migraine, asthma and headache.
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The juice of the berries is used in curing sore throat.
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The fumigation of Solanum xanthocarpum is helpful in piles.
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The herb is made to a paste and applied on swollen and painful joints to reduce the pain and swelling in arthritis.
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Roots and seeds are used as an expectorant in asthma, cough and pain in chest.
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The decoction of the root is given with honey, to treat cough.
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Its stem, flowers and fruits, being bitter and carminative, are used for relieving burning sensation in the feet.
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Solanum xanthocarpum fruits also facilitate seminal ejaculation, alleviate worms, itching, and fever and reduce fats.
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The fruit works as an aphrodisiac in males.
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The herb is helpful in treating respiratory disorders like bronchial asthma, cough and bronchitis
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Its seeds are helpful for treating irregular menstruation and dysmenorrheal in females.
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