Accession Number: pdtdbl00015

Details of the Ligand

Ligand Name : Vitamin A
Systematic Names : Retinol; Vitamin A; all-trans-Retinol; Vitamin A1; Alphalin; Axerophthol
Molecular Formula : C20H30O
Molecular Weight : g/mol
IUPAC Name : 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
Canonical SMILES : C=1(C(CCCC1C)(C)C)\C=C\C(=C\C=C\C(=C\CO)C)C
Ligand Description :
  • Vitamin A can be found in many fruits, vegetables, eggs, whole milk, butter, fortified margarine, meat, and oily saltwater fish. It can also be made in a laboratory.
  • Vitamin A is used for treating Vitamin A deficiency. It is also used to reduce complications of diseases such as malaria, HIV, measles, and diarrhea in children with vitamin A deficiency.
  • Women use Vitamin A for heavy menstrual periods, premenstrual syndrome (PMS), vaginal infections, yeast infections, “lumpy breasts” (fibrocystic breast disease), and to prevent breast cancer. Some women with HIV use Vitamin A to decrease the risk of transmitting HIV to the baby during pregnancy, childbirth, or breastfeeding.
  • Men use Vitamin A to raise their sperm count.
  • Some people use Vitamin A for improving vision and treating eye disorders including age-related macular degeneration (AMD), glaucoma, and cataracts.
  • Vitamin A is also used for skin conditions including acne, eczema, psoriasis, cold sores, wounds, burns, sunburn, keratosis follicularis (Darier’s disease), ichthyosis (noninflammatory skin scaling), lichen planus pigmentosus, and pityriasis rubra pilaris.
  • It is also used for gastrointestinal ulcers, Crohn’s disease, gum disease, diabetes, Hurler syndrome (mucopolysaccharidosis), sinus infections, hay fever, and urinary tract infections (UTIs).
  • Vitamin A is also used for shigellosis, diseases of the nervous system, nose infections, loss of sense of smell, asthma, persistent headaches, kidney stones, overactive thyroid, iron-poor blood (anemia), deafness, ringing in the ears, and precancerous mouth sores (leukoplakia).
  • Other uses include preventing and treating cancer, protecting the heart and cardiovascular system, slowing the aging process, and boosting the immune system.
  • Vitamin A is applied to the skin to improve wound healing, reduce wrinkles, and to protect the skin against UV radiation.
Related Plants :
Ligand Related Dockings :
NA
Ligand References :
  1. https://en.wikipedia.org/wiki/Vitamin_A
  2. https://pubchem.ncbi.nlm.nih.gov/compound/445354
  3. http://chem.sis.nlm.nih.gov/chemidplus/rn/11103-57-4
  4. http://www.chemspider.com/Chemical-Structure.393012.html
  5. http://www.webmd.com/vitamins-supplements/ingredientmono-964-VITAMIN+A.aspx?activeIngredientId=964&activeIngredientName=VITAMIN+A&source=2
Vitamin A

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