Accession Number: pdtdbl00139

Details of the Ligand

Ligand Name : Thymol
Systematic Names : Thymol; 2-Isopropyl-5-methylphenol; 3-p-Cymenol; 5-Methyl-2-isopropylphenol; 6-Isopropyl-m-cresol
Molecular Formula : C10H14O
Molecular Weight : g/mol
IUPAC Name : 5-methyl-2-propan-2-ylphenol
Canonical SMILES : CC1=CC(=C(C=C1)C(C)C)O
Ligand Description :

Thymol (also known as IPMP) is a natural monoterpene phenol derivative of cymene, found in oil of thyme, and extracted from Thymus vulgaris (common thyme) and various other kinds of plants as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties. Thymol also provides the distinctive, strong flavor of the culinary herb thyme, also produced from T. vulgaris.

Thymol has antimicrobial activity because of its phenolic structure, and has shown antibacterial activity against bacterial strains including Aeromoans hydrophila and Staphylococcus aureus. In addition Thymol demonstrate confidential post antibacterial effect against some microorganisms. This antibacterial activity is caused by inhibiting growth and lactate production, and by decreasing cellular glucose uptake. Thymol has been used in alcohol solutions and in dusting powders for the treatment of tinea or ringworm infections, and was used in the United States to treat hookworm infections. It is also used as a preservative in halothane, an anaesthetic, and as an antiseptic in mouthwash. When used to reduce plaque and gingivitis, thymol has been found to be more effective when used in combination with chlorhexidine than when used purely by itself. Thymol is also the active antiseptic ingredient in some toothpastes, such as Euthymol.

Related Plants :
Ligand Related Dockings :
NA
Ligand References :
  1. https://en.wikipedia.org/wiki/Thymol
  2. http://pubchem.ncbi.nlm.nih.gov/compound/thymol
  3. http://chem.sis.nlm.nih.gov/chemidplus/name/Thymol
Thymol

Click the image to enlarge