| Ligand Name : |
Rifampicin |
| Systematic Names : |
Rifampicin; Rifadin; Rifampin; Rimactane; Rimactan; Tubocin |
| Molecular Formula : |
C43H58N4O12 |
| Molecular Weight : |
g/mol |
| IUPAC Name : |
5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)-naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate |
| Canonical SMILES : |
CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C |
| Ligand Description : |
Rifampicin, also known as rifampin, is an antibiotic used to treat a number of bacterial infections. This includes tuberculosis, leprosy, and legionella, among others. Often it is used along with other antibiotics. Rifampicin is active against a variety of organisms including Staphylococcus aureus, Staphylococcus epidermidis, Mycobacterium tuberculosis, Mycobacterium leprae, Neisseria meningiditis and Brucella species.
Common side effects include nausea, vomiting, diarrhea, and loss of appetite. It may also turn urine, sweat, and tears a red color. Liver problems or allergic reactions may occur. It is part of the recommended treatment of active tuberculosis during pregnancy even though safety is not clear in pregnancy. Rifampicin is of the rifamycin group of antibiotics. It works by stopping the making of RNA by the bacteria |
| Related Plants : |
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| Ligand Related Dockings : |
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| Ligand References : |
- https://pubchem.ncbi.nlm.nih.gov/compound/Rifampicin
- http://www.chemspider.com/Chemical-Structure.10468813.html
- https://en.wikipedia.org/wiki/Rifampicin
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