Accession Number: pdtdbl00040

Details of the Ligand

Ligand Name : Procyanidin B2
Systematic Names : Procyanidin B2; Procyanidol B2; Proanthocyanidin B2
Molecular Formula : C30H26O12
Molecular Weight : g/mol
IUPAC Name : (2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
Canonical SMILES : C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O
Ligand Description :

Procyanidin B2 is a B type proanthocyanidin. Its structure is (−)-Epicatechin-(4β→8)-(−)-epicatechin.

Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chinensis (litchi, in the pericarp), in the apple, and in Ecdysanthera utilis.

Procyanidin B2 can be converted into procyanidin A2 by radical oxidation using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals under neutral conditions.

Procyanidin B2 has been shown to inhibit the formation of the advanced glycation end-products pentosidine, carboxymethyllysine (CML), and methylglyoxal (MGO).
Related Plants :
Apple
Ligand Related Dockings :
NA
Ligand References :
  1. https://en.wikipedia.org/wiki/Procyanidin_B2
  2. https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=122738
  3. http://chem.sis.nlm.nih.gov/chemidplus/name/procyanidin%20b2
Procyanidin B2

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