Avicularin is a bioactive flavonol isolated from a number of plants including Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi. It suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose uptake in 3T3-L1 cells.

The Guaijaverin (Gua) is a polyphenolic substance which exhibits some pharmacological activities such as antibacterial and antioxidant activities. Guaijaverin from leaves of guava has potential as an antiplaque agent due to its bacteriostatic property by inhibiting the growth of S. mutans and Staphylococcus aureus (S. aureus). Guaijaverin decreases the hydrophobicity, one of the most important initial factors for the oral pathogenic bacteria to adhere to the tooth surface. This action is possibly because guava extracts binds to the cell surface proteins reducing the overall cell hydrophobicity and hence guava may have potential for development as a natural antiplaque agent.