Ligand Name : |
Quercetin |
Systematic Names : |
Quercetin; Sophoretin; Meletin; Xanthaurine; Quercetine |
Molecular Formula : |
C15H10O7 |
Molecular Weight : |
g/mol |
IUPAC Name : |
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one |
Canonical SMILES : |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
Ligand Description : |
Quercetin is a plant pigment (flavonoid). It is found in many plants and foods, such as red wine, onions, green tea, apples, berries, Ginkgo biloba, St. John's wort, American elder, and others. Buckwheat tea has a large amount of quercetin. People use quercetin as a medicine.
Quercetin is used for treating conditions of the heart and blood vessels including “hardening of the arteries†(atherosclerosis), high cholesterol, heart disease, and circulation problems. It is also used for diabetes, cataracts, hay fever, peptic ulcer, schizophrenia, inflammation, asthma, gout, viral infections, chronic fatigue syndrome (CFS), preventing cancer, and for treating chronic infections of the prostate. Quercetin is also used to increase endurance and improve athletic performance.
Quercetin is a polyphenolic flavonoid with potential chemopreventive activity. Quercetin, ubiquitous in plant food sources and a major bioflavonoid in the human diet, may produce antiproliferative effects resulting from the modulation of either EGFR or estrogen-receptor mediated signal transduction pathways. Although the mechanism of action of action is not fully known, the following effects have been described with this agent in vitro: decreased expression of mutant p53 protein and p21-ras oncogene, induction of cell cycle arrest at the G1 phase and inhibition of heat shock protein synthesis. This compound also demonstrates synergy and reversal of the multidrug resistance phenotype, when combined with chemotherapeutic drugs, in vitro. Quercetin also produces anti-inflammatory and anti-allergy effects mediated through the inhibition of the lipoxygenase and cyclooxygenase pathways, thereby preventing the production of pro-inflammatory mediators. |
Other Related Plants : |
Adhatoda, Apple, Black Pepper, Eucalyptus, Jamun, Kandankathiri, Lady's Finger, Mango, Neem, Tomato, Valerian |
Ligand Related Dockings : |
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Plant Name : |
Onion |
Alternative Names : |
Shallot, வெஙà¯à®•ாயம௠|
Scientific Name : |
Allium cepa |
Medicinal Parts : |
Bulb |
Plant Category : |
Vegetable, Herb |
2° Metabolites (10/25) : |
Anthocyanins, Calcium, Carbohydrates, Cepaenes, Fat, Fluoride, Iron, Kaempferol, Magnesium, Manganese, Phosphorus, Potassium, Protein, Quercetin, Sodium, Thiosulfinates, Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B9, Vitamin C, Water, Zinc |
Phytochemical IDs : |
pdtdbl00087, pdtdbl00063, pdtdbl00038, pdtdbl00008, pdtdbl00009, pdtdbl00010, pdtdbl00011, pdtdbl00012, pdtdbl00013, pdtdbl00016 |
Plant Keywords : |
Onion, Allium cepa, Shallot, வெஙà¯à®•ாயம௠|
Plant Description : |
- Onion is used for treating digestion problems including loss of appetite, upset stomach, and gallbladder disorders; for treating heart and blood vessel problems including chest pain (angina) and high blood pressure; and for preventing “hardening of the arteries†(atherosclerosis). It is also used for treating sore mouth and throat, whooping cough, bronchitis, asthma, dehydration, intestinal gas, parasitic worms, and diabetes. Some people use it as a diuretic to increase urine output.
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Onion is applied directly to the skin for insect bites, wounds, light burns, boils, warts, and bruises.
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In foods, onion is used in many recipes.
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Many research investigation proves onion can be used to cure Stomach Cancer, Lung Cancer, Bladder Cancer, Colorectal Cancer, Breast Cancer, Ovarian Cancer, Brain Cancer, Bone Health, Diabetes, Coronary Heart Disease, Morphine Withdrawal, Immunosuppression, HIV, Cataracts.
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In manufacturing, the oil is used to flavor foods.
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